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BCN 2019, 10(1): 59-72 |
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Talimkhani A, Abdollahi I, Mohseni-Bandpei M A, Ehsani F, Khalili S, Jaberzadeh S. Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study. BCN 2019; 10 (1) :59-72
URL: http://bcn.iums.ac.ir/article-1-1057-en.html
URL: http://bcn.iums.ac.ir/article-1-1057-en.html
Ailin Talimkhani1 
, Iraj Abdollahi * 2, Mohammad Ali Mohseni-Bandpei3 , Fatemeh Ehsani4 , Sanaz Khalili5 , Shapour Jaberzadeh6
, Iraj Abdollahi * 2, Mohammad Ali Mohseni-Bandpei3 , Fatemeh Ehsani4 , Sanaz Khalili5 , Shapour Jaberzadeh6
1- Department of Physical Therapy, School of Rehabilitation Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
2- Department of Physical Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
3- Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
4- Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran.
5- Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
6- Non-invasive Brain Stimulation & Neuroplasticity Laboratory, Department of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
2- Department of Physical Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
3- Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
4- Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran.
5- Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
6- Non-invasive Brain Stimulation & Neuroplasticity Laboratory, Department of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.
Abstract:
Introduction: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals.
Methods: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions.
Results: Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05).
Conclusion: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field.
Methods: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions.
Results: Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05).
Conclusion: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field.
Keywords: Transcranial direct current stimulation, Primary motor cortex, Dorsolateral prefrontal cortex, Learning, Motor skills
Type of Study: Original |
Subject:
Clinical Neuroscience
Received: 2017/10/28 | Accepted: 2018/04/30 | Published: 2019/01/1
Received: 2017/10/28 | Accepted: 2018/04/30 | Published: 2019/01/1
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