● ^{Anxiety was the common negative emotion experienced by the participants who regularly checked the COVID-19-related news.}

● ^{Problem solving was the most frequent strategy used by the participants to regulate negative emotions.} 

● ^{Being directly involved with COVID-19 in personal life did not make any differences in the way that individuals emotionally respond to the news.}

● ^{Using Integrative approach in regulating emotions was found in more resilient individuals.}

^{Plain Language Summary} 

^{During the Coronavirus Disease 2019 (COVID-19) outbreak, news media has played an important role in providing people with latest updates on this stressful condition. Repeated exposure to such stressful news may elicit different emotions in people and engage them in using strategies to control their emotions. In this study, we aimed at exploring the most common negative emotion(s) experienced by individuals, as well as the most frequent Emotion Regulation strategies used facing the COVID-19-related news. We also examined whether the variable of personal relevance can moderate these emotional responses.}

● ^{Drug interactions are major challenge in comorbidity of psychiatric disorders and COVID-19 infection}

● ^{QTc prolongation is a major concern while using antiviral medications and/or Chloroquine/hydroxychloroquine in combination with many psychotropics. Cardiac monitoring especially in high risk patients is highly recommended.}

● ^{concomitant use of SSRIs with antiviral medications and/or Chloroquine/hydroxychloroquine increase the risk of hypoglycemia.} 

● ^{concomitant use of pimozide or midazolam with antiviral medications is contraindicated.} 

^{Plain Language Summary} 

^{In December 2019, the reports of coronavirus disease 2019 (COVID-19) were documented in Wuhan, China. This condition is caused by a novel beta-coronavirus, called as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2). Nowadays, the Coronavirus Disease 2019 (COVID-19) has become a global pandemic; with more than hundred thousand cases have been identified in Iran. COVID-19 affects people's mental health and quality of life. The COVID-19 causes panic, anxiety, depression and insomnia, especially in patients and health care professionals. There is a possibility of starting psychiatric drugs in patients with COVID-19. Also, some patients with COVID-19 have been taking psychiatric drugs due to various problems. As a result of this, the likelihood of drug- drug interaction (DDI) between psychiatric drugs and drugs used to treat COVID-19 can be a concern. Many psychiatric drugs are metabolized via the cytochrome P450 system. Therefore, their hepatic metabolism and ability to alter activity of cytochrome P450 can lead to pharmacokinetic interactions when they are used with medications in COVID-19 treatment. Risk of toxicity or lack of efficacy may occur due to higher or lower plasma concentration of medications. Moreover intensification of similar adverse effects might lead to patients harm. Psychiatric medication can be safe in combination with COVID-19 pharmacotherapy with close attention to selection of medication with the least possibility of interaction and also careful monitoring.}

● ^{COVID-19 influenced the lives of addicted patients in a way that is comparable with how we are all affected all by the pandemic.}

● ^{Because of the mostly negative thoughts, feelings and behavior the interviewees in treatment were vulnerable to relapse.}

● ^{Thoughts, feelings and behavior forms a good basis for a behavioral therapeutic intervention by making a functional analysis and challenging irrational thoughts and looking together for more rational thoughts that can reduce negative feelings.}

● ^{Therapy has changed by necessary rules to mitigate COVID-19 spread, and patient and health care worker both are troubled by it. Just as Shared Decision Making helps to start a treatment, improves the working alliance, the adherence and the efficacy, this method could very well be used to shape effective and receptive treatment interventions during the different challenges faced at different stages of the COVID-19 epidemic.} 

^{Plain Language Summary} 

^{On several occasions it was suggested that it would be good to make addicted patients' voices heard in this COVID-19 pandemic. Anecdotes are not suitable for this, so we conducted in the second week of April a qualitative study. We were able to develop a description and understanding of general and clinically relevant aspects of the impact of pandemic.  Interviewees shared anxieties about their health and the health of their relatives. Frightening thoughts were associated with a range of negative feelings and behaviors such as stress, anger, avoidance and isolation. The use of psychoactive substances differed between the patients in treatment with those who are in stable recovery. In the former all succeeded in staying abstinent. They have experienced that solidarity and connectedness were essential in sustaining their recovery. Those still in treatment were fighting against the temptation to start using again, they felt emotionally isolated and sometimes patronized by health care workers. The elaboration of the interviewees on the therapeutic relationship provides promising clues to optimize that relationship. "We are all in it together!" Shared Decision Making could very well be used to shape effective and receptive treatment interventions during the different challenges faced at different stages of the COVID-19 epidemic.}