Volume 15, Issue 3 (May & Jun 2024)
BCN 2024, 15(3): 287-300 |
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Bakizadeh F, Mokhtari S, Saeed F, Mokhtari A, Akbari Koli P, Shalbafan M. Cognitive Rehabilitation for Adult Patients With Obsessive-compulsive Disorder: A Systematic Review of Randomized Controlled Trials. BCN 2024; 15 (3) :287-300
URL: http://bcn.iums.ac.ir/article-1-2565-en.html
URL: http://bcn.iums.ac.ir/article-1-2565-en.html
Farah Bakizadeh1 
, Saba Mokhtari2 , Fahime Saeed3 , Asieh Mokhtari4 , Pouria Akbari Koli5 , Mohammadreza Shalbafan * 6
, Saba Mokhtari2 , Fahime Saeed3 , Asieh Mokhtari4 , Pouria Akbari Koli5 , Mohammadreza Shalbafan * 6
1- Department of Psychology, School of Psychology and Education, University of Tehran, Tehran, Iran.
2- Department of Psychiatry, School of Behavioral Sciences and Mental Health, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
3- Department of Psychiatry, Psychosis Research Center, School of Behavioral Sciences and Mental Health, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
4- Department of Laboratory Sciences, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
5- Department of Cognitive Rehabilitation, Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran.
6- Mental Health Research Center, Psychosocial Health Research Institute (PHRI), Iran University of Medical Sciences, Tehran, Iran.
2- Department of Psychiatry, School of Behavioral Sciences and Mental Health, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
3- Department of Psychiatry, Psychosis Research Center, School of Behavioral Sciences and Mental Health, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
4- Department of Laboratory Sciences, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.
5- Department of Cognitive Rehabilitation, Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran.
6- Mental Health Research Center, Psychosocial Health Research Institute (PHRI), Iran University of Medical Sciences, Tehran, Iran.
Abstract:
Introduction: Obsessive-compulsive disorder (OCD) is a disabling mental condition. Many studies have shown that OCD patients have cognitive deficits in various aspects of their cognition, which is a worsening factor of symptom severity, a potential endophenotype, insight predictor, and prognostic indicator of OCD. We designed this systematic review to evaluate the clinical efficacy of cognitive rehabilitation in cognitive deficits and symptom severity of patients with OCD following the PRISMA guidelines.
Methods: We searched PubMed, Scopus, ScienceDirect, Google Scholar, and Cochrane Library using the MeSH terms and keywords of ‘cognitive rehabilitation’ and ‘obsessive-compulsive disorder’. The database search identified 200 records of interest, and then 105 duplicates were removed from them. From 95 remaining studies, six articles were eligible for the study and met the inclusion criteria. The six articles described individual RCT studies representing a wide variety of study designs.
Results: The six included studies investigated the effect of “organizational training”, “cognitive remediation”, “attention splitting” and “goal management training” on cognitive impairments and symptom severity of OCD patients.
There are a small number of studies with different designs and some biases that have examined the effectiveness of cognitive rehabilitation in OCD patients, with conflicting results regarding the effect of cognitive rehabilitation on OCD symptom severity or cognitive deficit.
Conclusion: According to the results, we cannot conclude about the efficacy of cognitive rehabilitation in adults with OCD. Considering the importance of cognitive deficits in OCD patients, it is necessary to design and conduct standard trials to investigate the role of cognitive rehabilitation in these disorders.
Methods: We searched PubMed, Scopus, ScienceDirect, Google Scholar, and Cochrane Library using the MeSH terms and keywords of ‘cognitive rehabilitation’ and ‘obsessive-compulsive disorder’. The database search identified 200 records of interest, and then 105 duplicates were removed from them. From 95 remaining studies, six articles were eligible for the study and met the inclusion criteria. The six articles described individual RCT studies representing a wide variety of study designs.
Results: The six included studies investigated the effect of “organizational training”, “cognitive remediation”, “attention splitting” and “goal management training” on cognitive impairments and symptom severity of OCD patients.
There are a small number of studies with different designs and some biases that have examined the effectiveness of cognitive rehabilitation in OCD patients, with conflicting results regarding the effect of cognitive rehabilitation on OCD symptom severity or cognitive deficit.
Conclusion: According to the results, we cannot conclude about the efficacy of cognitive rehabilitation in adults with OCD. Considering the importance of cognitive deficits in OCD patients, it is necessary to design and conduct standard trials to investigate the role of cognitive rehabilitation in these disorders.
Type of Study: Review |
Subject:
Cellular and molecular Neuroscience
Received: 2022/10/16 | Accepted: 2022/11/12 | Published: 2024/05/1
Received: 2022/10/16 | Accepted: 2022/11/12 | Published: 2024/05/1
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