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1- Department of Neurosurgery, Iran University of Medical Sciences, Tehran, Iran.
2- Department of Neurosurgery, Mashhad University of Medical Sciences, Mashhad, Iran.
3- Department of Radiology Technology, School of Allied Medical Science, Shshid Beheshti University of Medical Science, Tehran, Iran.
Introduction : Magnetic resonance imaging (MRI) is the preferred neuroradiologic tool for evaluating the sellar region. Pituitary adenomas account for about 15% of primary intracranial tumors. The optimal time for post-operative MRI of CNS neoplasms is 48 hours after surgery. Nevertheless, controversy exists regarding the timing of post-operative MRI in the sellar region. This study analyzed the sellar MRI findings of patients with pituitary adenoma at different times before and after surgery. Finally, we suggest the optimal time for post-operative sellar MRI imaging in patients with pituitary adenoma. 
Materials and MethodsA total of 28 patients with pituitary adenoma were evaluated. All patients did four sellar MRIs; the first MRI was done before surgery, and three remainings were done as follows: 48 hours, two weeks, and three months after the surgery. Finally, the MRI findings at different times were compared to each other.
Results: We resulted that the pituitary gland and adenoma signals were constant in all sequences over time. The signal of the packing material showed no differences in T1-weighted and T1-weighted with contrast sequences but showed changes in T2-weighted sequences. 
Discussion:  In contrast to other intracranial neoplasms, in patients with pituitary adenoma, there were no apparent changes in MRI signal intensity during the 3-month after surgery. There was also no superiority of one time over another for performing follow-up imaging.

Type of Study: Original | Subject: Clinical Neuroscience
Received: 2022/11/23 | Accepted: 2023/04/4

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