Volume 14, Issue 1 (January & February-In Press 2023)                   BCN 2023, 14(1): 0-0 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Ahmadirad N, Bakhtiarzadeh F, Zare M, Ghasemi Z, Sadeghin A, Dehghan S et al . Neurostimulation as a Putative Method for Treatment of Drug-Resistant Epilepsy in Patient and Animal Models of Epilepsy. BCN 2023; 14 (1)
URL: http://bcn.iums.ac.ir/article-1-2507-en.html
Neurostimulation as a Putative Method for Treatment of Drug-Resistant Epilepsy in Patient and Animal Models of Epilepsy
Nooshin Ahmadirad *1, Fatemeh Bakhtiarzadeh2, Meysam Zare3, Zahra Ghasemi4, Azam Sadeghin2, Samaneh Dehghan5, Mohammad Taghi Joghataei6
1- Associate Research Scientist Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
2- Researcher Tarbiat Modares University, Department of Physiology, Tehran, Iran.
3- Researcher Stem cell and Regenerative Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.
4- Associate Research Scientist - Lunenfeld-Tanenbaum Research Institute, Toronto, Canada
5- Eye Research Center, the Five Senses Institute, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
6- Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Abstract:  
A patient with epilepsy was shown to have neurobiological, psychological, cognitive, and social issues as a result of recurring seizures, which is regarded to be a chronic brain disease.However, despite numerous drug treatments, approximately, 30–40% of all patients are resistant to antiepileptic drugs. Therefore, newer therapeutic modalities are introduced into clinical practice in which involve neurostimulation and direct stimulation of the brain. Hence, we review published literature regarding the vagus nerve stimulation, trigeminal nerve stimulation, applying responsive stimulation systems and DBS in animals and epileptic patient with an emphasis on drug-resistant epilepsy.
Keywords: Drug-resistant epilepsy, Vagus nerve stimulation, Trigeminal nerve stimulation, Responsive stimulation system, Deep brain stimulation
Full-Text [PDF 1611 kb]      
Type of Study: Review | Subject: Behavioral Neuroscience
Received: 2022/07/6 | Accepted: 2022/10/18 | Published: 2023/01/12
Add your comments about this article : Your username or Email:
CAPTCHA
Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Basic and Clinical Neuroscience

Designed & Developed by : Yektaweb