Volume 13, Issue 6 (November & December 2022)                   BCN 2022, 13(6): 893-900 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mirfazeli F S, Mohebi F, Jahanbakhshi A, Aryani O, Almasi-Dooghaee M. Repetitive Suicidal Behaviors in a Case With a New Mutation of Wolfram Syndrome: A Jump From the Gene to the Behavior. BCN 2022; 13 (6) :893-900
URL: http://bcn.iums.ac.ir/article-1-2233-en.html
1- Mental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran.
2- Department of Psychiatry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
3- Skull Base Research Center, Department of Neurosurgery, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
4- Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
5- Department of Neurology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Wolfram syndrome (WS) is a rare autosomal recessive neurodegenerative disease with variable symptoms, including neuropsychiatric manifestations. A 26-year-old man was reported with classic symptoms of WS and repetitive psychiatric hospitalizations and at least 16 suicidal attempts. The genetic study demonstrated a novel homozygous stop-codon mutation on the WFS1 gene. This special type of mutation may be related to repetitive suicidal behaviors in this case of WS. Psychological support should be a routine practice in patients with WS.
Type of Study: Original | Subject: Clinical Neuroscience
Received: 2021/04/18 | Accepted: 2021/08/23 | Published: 2022/11/1

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Basic and Clinical Neuroscience

Designed & Developed by : Yektaweb