Volume 10, Issue 6 (November & December 2019)                   BCN 2019, 10(6): 541-544 | Back to browse issues page

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Chirumbolo S. Is Mitochondria Biogenesis and Neuronal Loss Prevention in Rat Hippocampus Promoted by Apigenin?. BCN 2019; 10 (6) :541-544
URL: http://bcn.iums.ac.ir/article-1-1437-en.html
Department of Neuroscience, Biomedicine and Movement Sciences, Unit of Human Anatomy, University of Verona, Verona, Italy.
In this Correspondence, a comment to a recent paper by Nikbakht et al., published in the latest ssu of this Journal is reported. The flavone apigenin can exert both its anti-oxidant potetial via the usual enzymatic ROS scavenging system and the mitochondria biogenesis via the PGC-1α/ TFAM/NRF-1 pathway. The very interesting paper by Nikbakht et al, may earn more insighful clues about the activity of apigenin in the prevention of the rat hippocampus neuronal loss caused by the Aβ25-35 injection.
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Type of Study: Letter to Editor | Subject: Cellular and molecular Neuroscience
Received: 2019/02/19 | Accepted: 2019/04/6 | Published: 2019/11/1

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