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Acute Phase Reactants as a Prognostic Factor in Acute Stroke
Seyed Abbas Hasani, Seyed Ali Ziai, Masoud Mehrpour, Mandana Amiri, Mohamad R Motamed,
Volume 3, Issue 1 (10-2011)
Abstract

Introduction: Elevated levels of CRP are present among patients at risk for further first-ever myocardial infarction and stroke. It has been shown that after ischemic stroke, increased levels of CRP are associated with unfavorable outcomes.

Methods:

From 120 patients admitted to the emergency unit of our hospital with the diagnosis of stroke CRP, D-dimer and ferritin level was measured and the patients were followed until discharge or death.

Results:

CRP level was significantly different between the patients with TIA and stroke. D-Dimer level was also significantly different between the TIA & the admitted groups. Ferritin was not different between the prognosis groups. There was a correlation between CRP and D-Dimer (r = 0.381, p = 0.001), and also between CRP and ferritin (r = 0.478, p= 0.000).

Discussion:

CRP is a useful adjuvant marker to determine the prognosis of patients with cerebro-vascular events admitted to the hospital, in both patients with stroke positive history and first-ever stroke.


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