دوره 17، شماره 3 - ( 2-1405 )
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Zolghadr M, Sarrafzadeh J, Noorizadeh Dehkordi S, Talebian S, Yassin M, Haddadzade Niri H. Effects of Transcranial Direct Current Stimulation on EEG Mean Frequency and Motor Recovery in Chronic Stroke: A Randomized Controlled Study. BCN 2026; 17 (3)
URL: http://bcn.iums.ac.ir/article-1-3409-fa.html
URL: http://bcn.iums.ac.ir/article-1-3409-fa.html
Effects of Transcranial Direct Current Stimulation on EEG Mean Frequency and Motor Recovery in Chronic Stroke: A Randomized Controlled Study. مجله علوم اعصاب پایه و بالینی. 1405; 17 (3)
چکیده:
Objectives: This study aimed to investigate the effects of transcranial direct current stimulation (tDCs) on resting-state electroencephalography (EEG) mean frequency and motor recovery in patients with chronic stroke.
Methods: Thirty individuals with chronic stroke were randomly allocated to receive either real or sham anodal tDCs combined with task-oriented training (TOT). The real-tDCs group received 2 mA anodal stimulation over the motor cortex for 20 minutes per session, five times per week, for three weeks. EEG mean frequency and the Fugl-Meyer Assessment (FMA) of the upper extremity were used as the main and secondary outcomes, respectively.
Results: Both groups demonstrated a gradual reduction in EEG mean frequency over time, with a more pronounced decrease in the sham group. This difference was statistically significant only at follow-up (P = 0.02). The FMA scores improved significantly in both groups (P < 0.001), with a greater improvement trend in the real-tDCs group; however, intergroup differences were not significant.
Conclusion: Although the association between EEG mean frequency and motor performance remains inconclusive, these findings suggest that anodal tDCs may modulate cortical activity and support motor recovery in chronic stroke patients.
Methods: Thirty individuals with chronic stroke were randomly allocated to receive either real or sham anodal tDCs combined with task-oriented training (TOT). The real-tDCs group received 2 mA anodal stimulation over the motor cortex for 20 minutes per session, five times per week, for three weeks. EEG mean frequency and the Fugl-Meyer Assessment (FMA) of the upper extremity were used as the main and secondary outcomes, respectively.
Results: Both groups demonstrated a gradual reduction in EEG mean frequency over time, with a more pronounced decrease in the sham group. This difference was statistically significant only at follow-up (P = 0.02). The FMA scores improved significantly in both groups (P < 0.001), with a greater improvement trend in the real-tDCs group; however, intergroup differences were not significant.
Conclusion: Although the association between EEG mean frequency and motor performance remains inconclusive, these findings suggest that anodal tDCs may modulate cortical activity and support motor recovery in chronic stroke patients.
نوع مطالعه: Original |
موضوع مقاله:
Cognitive Neuroscience
دریافت: 1404/8/24 | پذیرش: 1404/10/16 | انتشار: 1405/2/28
دریافت: 1404/8/24 | پذیرش: 1404/10/16 | انتشار: 1405/2/28
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