Volume 10, Issue 3 (May & June 2019)                   BCN 2019, 10(3): 199-208 | Back to browse issues page

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Shiani A, Joghataei M T, Ashayeri H, Kamali M, Razavi M R, Yadegari F. Comprehension of Complex Sentences in the Persian-Speaking Patients With Aphasia. BCN. 2019; 10 (3) :199-208
URL: http://bcn.iums.ac.ir/article-1-841-en.html
1- Department of Radiology, Faculty of Allied Medical Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran.
2- Cellular and Molecular Research Center, Department of Anatomy, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
3- Department of Psychiatry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
4- Department of Basic Rehabilitation Sciences, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
5- Academy of Persian Language and Literature, Tehran, Iran.
6- Department of Speech Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Introduction: To study sentence comprehension in Persian-speaking Patients with Aphasia considering the factors of complexity.
Methods: In this cross-sectional study, the performance of 6 non-fluent aphasic patients were tested and their performance was compared to 15 matched control group. Comprehension of semantically reversible sentences was assessed using a binary sentence-picture matching task. The stimuli were as follows: clefts; subject clefts and object clefts, also relative clauses; subject relatives and object relatives. All of them were types of movement-derived structures and also simple declarative sentences as the control task.
Results: The best performance of aphasic patients were seen in the comprehension of subject clefts, although prior to this result we assumed that simple declarative sentences (in which there is no structural factor of complexity) can be understood easily. They showed the highest difficulty in the comprehension of object relatives. Furthermore, the performance of patients in the comprehension of relative clauses was significantly weaker than understanding the clefts.
Conclusion: The outcomes of this study suggest that the sentence comprehension deficits of aphasic patients, in contrast to the specific deficit models, may not be related to linguistic disabilities. Moreover, the problems in the comprehension of non-canonical sentences may be related to failure in the allocation of attention. Finally, our results support the claims that neural characterization of the cognitive resources (e.g. working memory) is disrupted in sentence comprehension deficits. 

Type of Study: Original | Subject: Behavioral Neuroscience
Received: 2016/10/3 | Accepted: 2018/04/30 | Published: 2019/07/21

1. Peters A, McEwen BS, Friston K. Uncertainty and stress: Why it causes diseases and how it is mastered by the brain. Progress in Neurobiology. 2017;156:164-88. [DOI:10.1016/j.pneurobio.2017.05.004] [PMID]
2. Hitze B, Hubold C, Van Dyken R, Schlichting K, Lehnert H, Entringer S, et al. How the selfish brain organizes its supply and demand. Frontiers in neuroenergetics. 2010;2:7. [DOI:10.3389/fnene.2010.00007] [PMID] [PMCID]
3. Moradi F, Mahdavi MRV, Ahmadiani A, Rogani M, Delshad AR, Mojarab S, et al. Social instability, food deprivation and food inequality can promote accumulation of lipofuscin and induced apoptosis in hepatocytes. World Applied Sciences Journal. 2012;20(2):310-8.
4. Azpiroz A, Garmendia L, Fano E, Sanchez-Martin JR. Relations between aggressive behavior, immune activity, and disease susceptibility. Aggression and violent behavior. 2003;8(4):433-53. [DOI:10.1016/S1359-1789(02)00066-6]
5. BIONDI M. Effects of stress on immune functions: an overview. Psychoneuroimmunology. 2001;2:189-226.
6. Rabin BS. Stress, immune function, and health: The connection: Wiley-Liss; 1999.
7. Petitto JM, Gariepy J-L, Gendreau PL, Rodriguiz R, Lewis MH, Lysle DT. Differences in NK cell function in mice bred for high and low aggression: genetic linkage between complex behavioral and immunological traits? Brain, behavior, and immunity. 1999;13(2):175-86. [DOI:10.1006/brbi.1998.0539] [PMID]
8. Aghajani M, Mahdavi MRV, Najafabadi MK, Ghazanfari T. The effect of social stress on chronic pain perception in female and male mice. PLOS one. 2012;7(10):e47218. [DOI:10.1371/journal.pone.0047218] [PMID] [PMCID]
9. Bailey MT, Kierstein S, Sharma S, Spaits M, Kinsey SG, Tliba O, et al. Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production. The journal of immunology. 2009;182(12):7888-96. [DOI:10.4049/jimmunol.0800891] [PMID] [PMCID]
10. Dhabhar FS. A hassle a day may keep the pathogens away: the fight-or-flight stress response and the augmentationof immune function. Integrative and comparative biology. 2009;49(3):215-36. [DOI:10.1093/icb/icp045] [PMID]
11. Hu D, Wan L, Chen M, Caudle Y, LeSage G, Li Q, et al. Essential role of IL-10/STAT3 in chronic stress-induced immune suppression. Brain, behavior, and immunity. 2014;36:118-27. [DOI:10.1016/j.bbi.2013.10.016] [PMID] [PMCID]
12. Silberman D, Ayelli-Edgar V, Zorrilla-Zubilete M, Zieher L, Genaro A. Impaired T-cell dependent humoral response and its relationship with T lymphocyte sensitivity to stress hormones in a chronic mild stress model of depression. Brain, behavior, and immunity. 2004;18(1):81-90. [DOI:10.1016/S0889-1591(03)00109-0]

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