Volume 8, Issue 3 (May & June 2017 -- 2017)                   BCN 2017, 8(3): 233-248 | Back to browse issues page


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Saremi A A, Shariat S V, Nazari M A, Dolatshahi B. Research Paper: Neuropsychological Functioning in Obsessive-Compulsive Washers: Drug-Naive Without Depressive Symptoms. BCN. 2017; 8 (3) :233-248
URL: http://bcn.iums.ac.ir/article-1-706-en.html
1- Department of Cognitive Neuroscience, Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
2- Mental Health Research Center, Tehran Institute of Psychiatry, School of Behavioural Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran.
3- Department of Psychology, Faculty of Education & Psychology, University of Tabriz, Tabriz, Iran.
4- Department of Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Abstract:  

Introduction: Obsessive–Compulsive Disorder (OCD) is a complex and heterogeneous neuropsychiatric syndrome. Contamination obsessions and washing/cleaning compulsions are the most frequent clinical OCD subtypes. The current study aimed at examining the neuropsychological impairments in drug-naive obsessive-compulsive (OC) washers without depressive symptoms and their association with the severity of symptoms.
Methods: In the current causal-comparative study, 35 patients with diagnostic and statistical mental disorders class (DSM)-IV diagnosed with washing-subtype OCD and 35 healthy subjects were selected by the convenience sampling method and evaluated by computerized neuropsychology battery and clinical tests as Stroop Color-Word Test (SCWT), Wisconsin Card Sorting Test (WCST), Go/No-Go Test, Digits Forward (DF), Digits Backward (DB), Yale-Brown Obsessive–Compulsive Scale (Y-BOCS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and General Health Questionnaire (GHQ)-28. The patients were matched to the comparison group with regard to age, gender, intelligence quotient (IQ), education, and handedness. All the tests were standardized in Iran. SPSS version 20.00 was used for descriptive and analytical data analysis.
Results: There was no statistically significant different between the OCD washing and the control groups regarding socio-demographic variables or IQ. There were significant differences between the OC washer and the healthy control groups on the neuropsychological functioning. The obtained results suggested that OC washers performed significantly worse on neuropsychological measures than the controls. There was no significant association between the severity of OC symptoms and the neuropsychological functions in the OCD washing group.
Conclusion: It was concluded that executive function impairment, which is a core feature in OC washers was trait-like in nature.

Type of Study: Original | Subject: Cognitive Neuroscience
Received: 2016/08/13 | Accepted: 2016/12/19 | Published: 2017/05/1

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