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1- Physical Medicine & Rehabilitation Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:  
Introduction: The sural to radial sensory nerve action potential amplitude ratio (SRAR) can serve as a criterion for diagnosing peripheral axonal neuropathy. However, different studies have revealed varying lowest values of this index. This research aimed to identify the minimum normal value of SRAR in healthy individuals and evaluate the impact of age, gender, height, weight, body mass index (BMI), forearm length, wrist circumference, ankle circumference, and leg length on the lowest normal value of SRAR to distinguish between healthy people and those with axonal polyneuropathy.
Methods: The study involved 108 individuals referred for four-limb electrodiagnostic tests with normal results. The participants were between 20 and 70 years old, and the study was conducted between July 2022 and December 2023.  An electrodiagnosis test was carried out to determine the range of sural and radial sensory nerves. The data were analyzed using SPSS version 26, and a p-value of less than 0.05 was considered statistically significant.
Results: The study revealed that the lowest value of SRAR was 0.2 (mean = 0.435 ± 0.175). According to the Pearson correlation test, the SRAR has no significant correlation with age, BMI, forearm length, wrist circumference, ankle circumference, and leg length
Discussion: The study found that the SRAR was not affected by various physical characteristics such as age, gender, height, weight, forearm length, wrist circumference, ankle circumference, or leg circumference, and an SRAR value of 0.2 was the minimum normal value of SRAR in our healthy subjects.
Type of Study: Original | Subject: Clinical Neuroscience
Received: 2024/05/24 | Accepted: 2025/01/22

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