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Nervous System Stem Cell Research Center, Department of Anatomy, Faculty of Medicine, Semnan University of Medical Science, Semnan, Iran.
Several signaling pathways and transcription factors control the cell fate in development and differentiation in vitro. The orchestrated use of these factors results in cell specification. In co-culturing methods, many of these factors secreted by host cells and will lead the process. Today, transcription factors required for retinal progenitor cells are well the generation of these cells mesenchymal stem cells is an ideal goal. The purpose of the paper is to review novel methods for retinal progenitor production by selecting a set of signaling molecules in the presence of adult retinal pigment epithelium and acting as inducers of retinal cell differentiation.  
Type of Study: Review | Subject: Cellular and molecular Neuroscience
Received: 2018/07/16 | Accepted: 2020/02/2 | Published: 2018/03/15

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