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1- Faculty of Advance Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran; Student Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
2- National Center of Epidemiology and CIBERNED, Carlos III Institute of Health, Madrid, Spain
3- Department of Neurology, Rasoul Akram Hospital, Iran University of Medical Science, Tehran, Iran
4- Department of Occupational Therapy, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
5- Department of Occupational Therapy, School of Paramedical and Health, Zanjan University of Medical Sciences, Zanjan, Iran
6- Sport Injury Department, Faculty of Physical Education and Sport Sciences, Bu Ali Sina University, Hamedan, Iran
7- Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
8- Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran, 2.Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
Abstract:  
Introduction: In the elderly, functional balance, fear of falling and independence in activities of daily living are interrelated; however, this association may change under the influence of drug phase and the severity of disease in individuals with idiopathic Parkinson's disease. The aim of this study was to investigate the relationship between functional balance, fear of falling and independence in activities of daily living in drug on- and off-phase.
Methods: One hundred forty patients with Parkinson's Disease [F1] [F2] (mean age ± SD; 60.51± 12.32 years) were evaluated in terms of functional balance, fear of falling and independence in activities of daily living using the Berg Balance Scale, Fall Efficacy Scale-International, and Unified Parkinson Disease Rating Scale–activities of daily living, respectively, in drug on- and off -phases. Global disease rating was recorded by Hoehn and Yahr scale. Spearman coefficient, Kruskal-Wallis and Mann-Whitney tests were used to find out if the distribution of scale scores differs among levels of functional balance or among levels of disease severity.
Results: A strong correlation was found between the functional balance, fear of falling and independence in activities of daily living in both drug phases. The results also showed the significant difference in distribution of the Fall Efficacy Scale-International and Unified Parkinson Disease Rating Scale–activities of daily living scores among levels of functional balance (except independence in activities of daily living in drug off-phase). Also the distribution of the scores of Berg Balance Scale, Fall Efficacy Scale-International and Unified Parkinson Disease Rating Scale-activities of daily living showed significant differences among levels of disease severity.
 Conclusion: The study showed a strong correlation between functional balance, fear of falling and independence in activities of daily living that can be affected by drug phase and severity of the disease. However, more studies are needed to understand this relationship.
Type of Study: Original | Subject: Behavioral Neuroscience
Received: 2018/04/30 | Accepted: 2018/11/5

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