Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1396
12
1
gregorian
2018
3
1
9
2
online
1
fulltext
en
Sleep Architecture in Patients With Primary Snoring and Obstructive Sleep Apnea
Clinical Neuroscience
Clinical Neuroscience
Original
Original
<p style="text-align: justify;"><strong>Introduction: </strong>This study aimed to investigate sleep architecture in patients with primary snoring and obstructive sleep apnea.<br>
<strong>Methods: </strong>In this study, we analyzed polysomnographic data of 391 clients who referred to Sleep Disorders Research Center (SDRS). These people were classified into three groups based on their Apnea-Hypopnea Index (AHI) and snoring; control, Primary Snoring (PS), and Obstructive Sleep Apnea (OSA) group. Sleep architecture variables were then assessed in all groups.<br>
<strong>Results: </strong>The results of this study indicated a decrease in deep sleep or Slow Waves Sleep (SWS) and increase in light sleep or stage 1 of non-REM sleep (N1) in OSA patients compared with the control and PS groups. After controlling the effects of confounding factors, i.e. age and Body Mass Index (BMI) (which was performed through multiple regression analysis) significant differences were observed among the three groups with regard to N1. However, with regard to SWS, after controlling confounding variables (age and BMI), no significant difference was found among the groups.<br>
<strong>Conclusion:</strong> The results indicated that OSA, regardless of age and BMI, may increase light (N1) sleep possibly via a decline in blood oxygen saturation (SpO2). Such increase in N1 may be responsible for brain arousal. In addition, by controlling confounding factors (age and BMI), OSA did not affect SWS in OSA patients. However, further research is necessary to determine sleep architecture in more detail in the patients with OSA.</p>
Obstructive sleep apnea, Primary snoring, Sleep architecture, Polysomnography
147
156
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1061-1&slc_lang=en&sid=1
Kaveh
Shahveisi
K.shahveisi@kums.ac.ir
13700319475328460014065
13700319475328460014065
No
Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Amir
Jalali
a_jalali@kums.ac.ir
13700319475328460014066
13700319475328460014066
No
Department of Psychiatric Nursing, Faculty of Nursing & Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mohammad Raman
Moloudi
x.moloudi@gmail.com
13700319475328460014067
13700319475328460014067
No
Neurosciences Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Shahla
Moradi
shahla.mo55@gmail.com
13700319475328460014068
13700319475328460014068
No
Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Azad
Maroufi
13700319475328460014069
13700319475328460014069
No
Neurosciences Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Habibolah
Khazaie
hakhazaie@gmail.com
13700319475328460014070
13700319475328460014070
Yes
Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.