Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1389
8
1
gregorian
2010
11
1
2
1
online
1
fulltext
en
Effect of Protein Malnutrition on Efferent Projections of Amygdala to the Hippocampus
Cellular and molecular Neuroscience
Cellular and molecular Neuroscience
Original
Original
<strong>ABSTRACT</strong><p style="DIRECTION: ltr" align="justify"><strong><font color="#211d1e" size="2"><font color="#211d1e" size="2">Introduction: </font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">Previous investigations have shown that protein malnutrition can alters the structure and function of some areas of hippocampal formation. We investigated the effect of protein malnutrition on amygdaloid projections to the CA1 hippocampal area. In this study we investigated level and pattern of distribution of efferent projections from amygdala to hippocampus in the rat by Horseradish Peroxidas (HRP) neural tract tracing in 2 groups Control group fed with regular diet (% 18 proteins)and case group fed with low protein diet (%8). We used SPSS 11.0 (T test & mann-withney) Software for data analysis.</font></font></font></strong><font color="#211d1e" size="2"><font color="#211d1e" size="2"><p style="DIRECTION: ltr" align="justify"><strong>Methods: </strong></p></font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">Following injection of HRP to CA1 region of hippocampus in the control group Rats, Labelled neurons showed more density in the Basolateral, Cortical and Medial nuclear Groups. Having done the analysis and examining the relations between the case data and those of the control groups, we found that number of labelled neurons in the Basolateral, Cortical & medial nuclei were decreased in the case group(p<0.05). Our findings showed that different nuclei of amygdala (Basolateral, Cortical and Medial) send projections to CA1 region of hippocampus Among, them basolateral nuclei group send the most projections . </font></font></font><font color="#211d1e" size="2"><font color="#211d1e" size="2"><p style="DIRECTION: ltr" align="justify"><strong>Discussion: </strong></p></font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">This results may be caused by decrease of activity of neural cells after protein malnutrition, that can results in impairment in growth and development of nervous system. Also it is possible that axoplasmic transfer rate maybe decreased in this condition.</font></font></font></p>
Hippocampus, Amygdala,Protein Malnutrition.
37
43
http://bcn.iums.ac.ir/browse.php?a_code=A-10-2-8&slc_lang=en&sid=1
Gholamreza
Hassanzadeh
137003194753284600558
137003194753284600558
Yes
Mitra
Barzroodi pour
137003194753284600559
137003194753284600559
No
Mohammad
Bayat
137003194753284600560
137003194753284600560
No
Miriam
Javadi
137003194753284600561
137003194753284600561
No