Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1389
8
1
gregorian
2010
11
1
2
1
online
1
fulltext
en
P300 Component Modulation During a Go/Nogo Task in Healthy Children
Cellular and molecular Neuroscience
Cellular and molecular Neuroscience
Original
Original
<p style="DIRECTION: ltr" align="left"><strong>ABSTRACT </strong></p><p align="justify"><b><font color="#211d1e" size="2"><font color="#211d1e" size="2">Introduction: </font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">Several differences in the P300 component are observed when responses must be executed or inhibited in the Go/Nogo task. However, few studies were established by using well-controlled task with respect to the preparatory processing and stimulus probability. In the present study, we examined the peak amplitude and latency of Go-P300 (P300 evoked by visual Go stimuli) and Nogo-P300 (P300 evoked by visual Nogo stimuli) component in healthy children. </font></font></font><b><font color="#211d1e" size="2"><font color="#211d1e" size="2"><p align="justify">Methods: </p></font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">High resolution EEG data were recorded from 13 children (7-11 years old) during a cued equiprobable Go/Nogo task. The P300 component was measured at frontal (F3, Fz, F4) and parietal (P3, Pz, P4) regions in response to both Go and Nogo stimuli. Data were analyzes using a three-way repeated measures ANOVA.</font></font></font><b><font color="#211d1e" size="2"><font color="#211d1e" size="2"><p align="justify">Results: </p></font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">These children displayed higher P300 amplitude in the Go relative to Nogo condition at parietal region. In addition, decrease in P300 latency was observed at the frontal in comparison to parietal region.</font></font></font><b><font color="#211d1e" size="2"><font color="#211d1e" size="2"><p align="justify">Discussion: </p></font></font><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman"><font color="#211d1e" size="2" face="Times New Roman,Times New Roman">The results might suggest that the P300 is related to different processes or arise from different generators in execution and inhibition conditions.</font></font></font></b></b></b></b></p>
ERP,P300,Go/Nogo Task,Healthy Children.
31
36
http://bcn.iums.ac.ir/browse.php?a_code=A-10-2-7&slc_lang=en&sid=1
Mohammad Ali
Nazari
137003194753284600545
137003194753284600545
Yes
Fabrice
Wallois
137003194753284600546
137003194753284600546
No
Ardalan
Aarabi
137003194753284600547
137003194753284600547
No
Masoud
Nosratabadi
137003194753284600548
137003194753284600548
No
Patrick
Berquin
137003194753284600549
137003194753284600549
No