Basic and Clinical Neuroscience Journal

en P300 Component Modulation During a Go/Nogo Task in Healthy Children Cellular and molecular Neuroscience Cellular and molecular Neuroscience Original Original ABSTRACT Introduction: Several differences in the P300 component are observed when responses must be executed or inhibited in the Go/Nogo task. However, few studies were established by using well-controlled task with respect to the preparatory processing and stimulus probability. In the present study, we examined the peak amplitude and latency of Go-P300 (P300 evoked by visual Go stimuli) and Nogo-P300 (P300 evoked by visual Nogo stimuli) component in healthy children. Methods: High resolution EEG data were recorded from 13 children (7-11 years old) during a cued equiprobable Go/Nogo task. The P300 component was measured at frontal (F3, Fz, F4) and parietal (P3, Pz, P4) regions in response to both Go and Nogo stimuli. Data were analyzes using a three-way repeated measures ANOVA.Results: These children displayed higher P300 amplitude in the Go relative to Nogo condition at parietal region. In addition, decrease in P300 latency was observed at the frontal in comparison to parietal region.Discussion: The results might suggest that the P300 is related to different processes or arise from different generators in execution and inhibition conditions. ERP,P300,Go/Nogo Task,Healthy Children. 31 36 http://bcn.iums.ac.ir/browse.php?a_code=A-10-2-7&slc_lang=en&sid=1 Mohammad Ali Nazari 137003194753284600545 137003194753284600545 Yes Fabrice Wallois 137003194753284600546 137003194753284600546 No Ardalan Aarabi 137003194753284600547 137003194753284600547 No Masoud Nosratabadi 137003194753284600548 137003194753284600548 No Patrick Berquin 137003194753284600549 137003194753284600549 No