Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1393
11
1
gregorian
2015
2
1
6
1
online
1
fulltext
en
Inter-pulse Interval Affects the Size of Single-pulse TMS-induced Motor Evoked Potentials: a Reliability Study
Clinical Neuroscience
Clinical Neuroscience
Original
Original
<b>
Introduction: </b><div>Measuring the size of motor evoked potentials (MEPs) induced by transcranial
magnetic stimulation (TMS) is an investigational technique to show the level of corticospinal
excitability however, some of the fundamental methodological aspects of TMS (such as the
effects of inter-pulse intervals (IPI) on MEP size) are not fully understood, this issue raises
concerns about the reliability of MEPs, especially in pre-test post-test studies. </div><div><b>Methods:</b> MEP size at short and long IPIs was assessed during two separate sessions. Inter- and
intra-session reliability of MEP size also was assessed at both short and long IPIs. </div><div><b>Results:</b> The results indicated that long IPIs induced larger MEPs (p < 0.05) across all time points.
The intra-class correlation coefficient (ICC) indicated high intra- and inter-session reliability for
short (0.87 to 0.96) and long (0.80 to 0.97) IPIs respectively. The amplitude of MEPs also had
high intersession reliability for short (ICC = 0.87) and long (ICC = 0.80) IPIs. </div><div><b>Conclusion:</b> This study provides evidence that the length of IPIs determines the size of MEPs. As
a result, it is recommended to add the length of IPI to the international checklist of considerations
for TMS application.
</div>
Transcranial magnetic stimulation, Motor evoked potential, TMS application checklist, Reliability
44
51
http://bcn.iums.ac.ir/browse.php?a_code=A-10-567-1&slc_lang=en&sid=1
Bita
Vaseghi
bita.vaseghi@monash.edu.au
1370031947532846005483
1370031947532846005483
Yes
Monash University
Shapour
Jaberzadeh
shapour.jaberzadeh@monash.edu
1370031947532846005484
1370031947532846005484
No
Monash University
Maryam
Zoghi
mzoghi@unimelb.edu.au
1370031947532846005485
1370031947532846005485
No
Melbourne University