en Cellular and molecular Neuroscience Cellular and molecular Neuroscience Original Original <p>Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose his/her feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene defect. Direct sequencing was performed to screen NTRK1 for mutations. The result revealed a homozygous deletion of adenine on intron 14 that may cause the disease.</p> 88 90 http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-141&slc_lang=en&sid=1 Nasrollah Saleh-gohari 1370031947532846006539 1370031947532846006539 Yes Genetic Department, Medical School, Kerman University of Medical Sciences, Kerman, Iran. Marzye Mohammadi-Anaie 1370031947532846006540 1370031947532846006540 No Genetic Laboratory, Afzalipour Hospital, Kerman, Iran.