en Clinical Neuroscience Clinical Neuroscience Review Review <div style="text-align: justify;"><strong>Introduction</strong>: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with symptoms appearing from early childhood. Behavioral modifications, special education, and medicines are used to treat ASD; however, the effectiveness of the treatments depends on early diagnosis of the disorder. The primary approach in diagnosing ASD is based on clinical interviews and valid scales. Still, methods based on brain imaging could also be possible diagnostic biomarkers for ASD.&nbsp;<br> <strong>Methods</strong>: To identify the amount of information the functional magnetic resonance imaging (fMRI) reveals on ASD, we reviewed 292 task-based fMRI studies on ASD individuals. This study is part of a systematic review with the registration number CRD42017070975.<br> <strong>Results</strong>: We observed that face perception, language, attention, and social processing tasks were mainly studied in ASD. In addition, 73 brain regions, nearly 83% of brain grey matter, showed an altered activation between the ASD and normal individuals during these four tasks, either in a lower or a higher activation.&nbsp;<br> <strong>Conclusion</strong>: Using imaging methods, such as fMRI, to diagnose and predict ASD is a great objective; research similar to the present study could be the initial step.</div> Functional magnetic resonance imaging, Examinations and diagnoses, Autism 585 604 http://bcn.iums.ac.ir/browse.php?a_code=A-10-1774-3&slc_lang=en&sid=1 Seyed Amir Hossein Batouli batouli@sina.tums.ac.ir 13700319475328460046647 13700319475328460046647 No Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. Foroogh Razavi forooghrazavi@gmail.com 13700319475328460046648 0009-0006-3913-135X No Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran. Minoo Sisakhti mno.cs1369@gmail.com 13700319475328460046649 13700319475328460046649 No Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran. Zeinab Oghabian z_oghabian@yahoo.com 13700319475328460046650 0009-0003-6071-0055 No Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran. Haady Ahmadzade haady.ahmadzade@gmail.com 13700319475328460046651 0009-0005-5733-7696 No Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. Mehdi Tehrani Doost tehranid@tums.ac.ir 13700319475328460046652 13700319475328460046652 Yes Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.