en Cellular and molecular Neuroscience Cellular and molecular Neuroscience Original Original <div style="text-align: justify;"><strong>Introduction: </strong>Activities of Daily Living (ADL), as an ultimate goal of rehabilitation, rely on cultural and environmental factors. This study aimed to develop a questionnaire based on the occupational therapy practice frame to accurately evaluate Iranian children&rsquo;s occupational performance.<br> <strong>Methods:</strong> This scale was developed in two phases of planning and construction. The planning phase involved a literature review and a collection of the available evaluation tools in the area. The advice of two expert panels was used to develop a preliminary 87-item questionnaire. In the construction phase, 40 parents were surveyed to assess the popularity of the activities in Iran. After a face to content validation, the final version of the questionnaire was prepared with 93 items.<br> <strong>Results:</strong> The final 93-item questionnaire was used to assess the ADL of 3-6-year-old children. The 93 items, selected according to criteria found in the literature and the panel of experts, were categorized into six ranges of occupational therapy practice framework (bathing/washing/personal hygiene, toileting, dressing, eating/feeding, functional mobility, and others).<br> <strong>Conclusion: </strong>The ADL in Iranian children is a practical and culturally relevant tool for measuring the occupational performance of Iranian children. It can be used in clinical and population-based research.&nbsp;</div> Scale development, Activities of daily living, Children, Outcome measure 837 848 http://bcn.iums.ac.ir/browse.php?a_code=A-10-2732-1&slc_lang=en&sid=1 Hossein Soltaninejad soltaninejad56@gmail.com 13700319475328460052921 13700319475328460052921 No Department of Occupational Therapy, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Mehdi Alizadeh Zarei mehdii.alizadeh@yahoo.com 13700319475328460052922 13700319475328460052922 Yes Department of Occupational Therapy, Rehabilitation Research Center, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Malahat Akbarfahimi fahresident@gmail.com 13700319475328460052923 13700319475328460052923 No Department of Occupational Therapy, Rehabilitation Research Center, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Akram Azad azad.a@iums.ac.ir 13700319475328460052924 13700319475328460052924 No Department of Occupational Therapy, Rehabilitation Research Center, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran. Farzad Rabiei rabiei.farzad12@gmail.com 13700319475328460052925 13700319475328460052925 No Department of Occupational Therapy, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.