Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1398
6
1
gregorian
2019
9
1
10
5
online
1
fulltext
en
Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and Meta-analysis
Behavioral Neuroscience
Behavioral Neuroscience
Review
Review
<div style="text-align: justify;"><strong>Introduction</strong>: The present systematic review and meta-analysis aims to investigate the role of Posterior Tibial Nerve Stimulation (PTNS) in the control of fecal incontinence (FI).<br>
<strong>Methods</strong>: Two independent reviewers extensively searched in the electronic databases of Medline, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, CINAHL, and Scopus for the studies published until the end of 2016. Only randomized clinical trials were included. The studied outcomes included FI episodes, FI score, resting pressure, squeezing pressure, and maximum tolerable pressure. The data were reported as Standardized Mean Differences (SMD) with 95% confidence interval.<br>
<strong>Results</strong>: Five articles were included in the present study (249 patients under treatment with PTNS and 239 in the sham group). Analyses showed that PTNS led to a significant decrease in the number of FI episodes (SMD=-0.38; 95% CI: -0.67-0.10; P=0.009). Yet, it did not have an effect on FI score (SMD=0.13; 95% CI: -0.49-0.75; P=0.68), resting pressure (SMD=0.12; 95% CI: -0.14-0.37; P=0.67), squeezing pressure (SMD=-0.27; 95% CI: -1.03-0.50; P=0.50), and maximum tolerable pressure (SMD=-0.10; 95% CI: -0.40-0.24; P=0.52).<br>
<strong>Conclusion</strong>: Based on the results, it seems that the prescription of PTNS alone cannot significantly improve FI.</div>
Fecal incontinence, Tibial nerve, Electrical nerve stimulation, Tibial neuromodulation
419
432
http://bcn.iums.ac.ir/browse.php?a_code=A-10-562-1&slc_lang=en&sid=1
Arash
Sarveazad
arashsarveazad@gmail.com
13700319475328460024294
13700319475328460024294
No
Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Asrin
Babahajian
babahajian3@yahoo.com
13700319475328460024295
13700319475328460024295
No
Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Naser
Amini
aminon@iums.ac.ir
13700319475328460024296
13700319475328460024296
No
Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Jebreil
Shamseddin
shams.jebreil@gmail.com
13700319475328460024297
13700319475328460024297
No
Molecular Medicine Research Center, Hormozgan Health Institute, Department of Parasitology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Mahmoud
Yousefifard
yousefifard20@gmail.com
13700319475328460024298
13700319475328460024298
Yes
Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.