Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1397
10
1
gregorian
2019
1
1
10
1
online
1
fulltext
en
Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study
Clinical Neuroscience
Clinical Neuroscience
Original
Original
<div style="text-align: justify;"><strong>Introduction: </strong>Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals.<br>
<strong>Methods: </strong>In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions. <br>
<strong>Results:</strong> Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05). <br>
<strong>Conclusion:</strong> These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field. </div>
Transcranial direct current stimulation, Primary motor cortex, Dorsolateral prefrontal cortex, Learning, Motor skills
59
72
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1244-2&slc_lang=en&sid=1
Ailin
Talimkhani
ai.talimkhani@gmail.com
13700319475328460019956
13700319475328460019956
No
Department of Physical Therapy, School of Rehabilitation Sciences, Hamadan University of Medical Sciences, Hamadan, Iran.
Iraj
Abdollahi
irajabdollahi@hotmail.com
13700319475328460019957
13700319475328460019957
Yes
Department of Physical Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Mohammad Ali
Mohseni-Bandpei
Mohseni_Bandpei@yahoo.com
13700319475328460019958
13700319475328460019958
No
Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Fatemeh
Ehsani
fatemehehsani59@yahoo.com
13700319475328460019959
13700319475328460019959
No
Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Sanaz
Khalili
Sanazkhalili94@gmail.com
13700319475328460019960
13700319475328460019960
No
Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Shapour
Jaberzadeh
Shapour.jaberzadeh@monash.edu
13700319475328460019961
13700319475328460019961
No
Non-invasive Brain Stimulation & Neuroplasticity Laboratory, Department of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia.