en Cognitive Neuroscience Cognitive Neuroscience Original Original <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="font-weight:bold"><span style="font-weight:normal">Epilepsy is a neurological disorder characterized by abnormal electrical activity in the brain that leads to recurrent seizures. Many aspects of the analysis of epileptic seizures are still at the pre-clinical animal study phase. Electroencephalogram (EEG) is widely used in epileptic seizures diagnosis, but visual inspection of EEG analysis is often difficult and time-consuming. Therefore, the use of signal processing approaches and feature extraction from EEG signals for automatic epilepsy diagnosis is of great importance. Among all signal processing approaches, deep learning approaches offer a promising way to effectively identify EEG signal features in order to minimize the detection error and accelerate signal processing. This study aims to propose a novel CNN-based model to diagnose epileptic events from recurrence plots (RPs) rodent models. First, RPs were extracted using optimized phase-space parameters. Then, a convolutional neural network (CNN) model was designed to detect eoileptic events. Accuracy, Precision, Recall, F1 Score and specificity were also used to evaluate model. The results showed that the proposed method achieved promising classification accuracy of 98.2% and Precision, Recall, and F1 score above 0.80 (80%), which was suitable for seizure detection. The findings of this study demonstrate the effectiveness of the proposed CNN-based model for diagnosing epileptic events from RPs. The model&#39;s promising performance suggests that it could significantly aid in the automated diagnosis of epilepsy in animal models. It has the potential to reduce the time and effort required for manual analysis while maintaining high accuracy in pre-clinical research.</span></span></span></span><br> &nbsp;</div> Epileptic Seizures, Electroencephalogram (EEG), Convolutional Neural Network (CNN) 0 0 http://bcn.iums.ac.ir/browse.php?a_code=A-10-7042-2&slc_lang=en&sid=1 Shahed Salehzehi Shahed.Salehzehi@gmail.com 13700319475328460057551 13700319475328460057551 No Department of Research Center of Biomedical Engineering, Ma.C. Islamic Azad University of Mashhad , Iran. Parisa Hosseini Parisa.Hosseini@gmail.com 13700319475328460057552 13700319475328460057552 No Department of Research Center of Biomedical Engineering, Ma.C. Islamic Azad University of Mashhad , Iran. Ali koohian Mohammad abadi Ali.koohianMohammadabadi@gmail.com 13700319475328460057553 13700319475328460057553 No Department of Research Center of Biomedical Engineering, Ma.C. Islamic Azad University of Mashhad , Iran. Saleh Lashkari Saleh.Lashkari@gmail.com 13700319475328460057554 13700319475328460057554 No Department of Biomedical Engineering, Imam Reza International University , Mashhad, Iran. Hamid Reza Kobravi HamidReza.Kobravi@gmail.com 13700319475328460057555 13700319475328460057555 No Research Center of Biomedical Engineering, Ma.C. Islamic Azad University of Mashhad, Iran. Elias Mazrooei Rad Elias Mazrooei Rad 13700319475328460057556 13700319475328460057556 Yes Department of Biomedical Engineering, Khavaran Institute of Higher Education, Mashhad, Iran.