Basic and Clinical Neuroscience Journal

en Unusual Presentation of the Rathke Cleft Cyst: A 25-Year-Old Female Clinical Neuroscience Clinical Neuroscience News and Reports News and Reports <div style="text-align: justify;">Introduction: Rathke cleft cysts (RCC’s) are cystic sellar and supra sellar benign lesions which are thought to originate from the remnants of Rathke’s pouch. There are no specific clinical or radiological signs to differentiate them from other pituitary lesions. Presentation of Case: We report a 25-year-old female presented with hyperandrogenism and menstrual disorder, with the preliminary diagnosis of pituitary adenoma, based on clinic or radiologic features. The patient underwent endoscopic trans-sphenoid surgery, with the final histopathologic diagnosis of   Rathke cleft cyst. Discussion: Rathke cleft cysts (RCC) are generally asymptomatic, and the most common clinical findings are headache, pituitary dysfunction and visual disturbances It is important to diagnose the patient's problem at an early stage, based on the history, hormone profile, laboratory and radiologic findings. Conclusion: The presented case highlights the challenging pre-operative diagnosis of Rathke’s cyst.</div> Rathke cleft cyst, Sellar and supra sellar lesions, Endoscopic trans-sphenoid surgery 0 0 http://bcn.iums.ac.ir/browse.php?a_code=A-10-1187-3&slc_lang=en&sid=1 Zahra Davoudi dr.davoudi@sbmu.ac.ir 13700319475328460059072 13700319475328460059072 No Skull Base Research Center, Loghman Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Arezoo Chouhdari chouhdariarezoo@gmail.com 13700319475328460059073 13700319475328460059073 No Skull Base Research Center, Loghman Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Shahram Sabeti sabeti_shahram@yahoo.com 13700319475328460059074 13700319475328460059074 No Department of Pathology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammad Samadian mdsamadian@hotmail.com 13700319475328460059075 13700319475328460059075 Yes Skull Base Research Center, Loghman Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.