Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1395
12
1
gregorian
2017
3
1
8
2
online
1
fulltext
en
Assessment of Executive Functions in Methamphetamineaddicted Individuals: Emphasis on Duration of Addiction and Abstinence
Behavioral Neuroscience
Behavioral Neuroscience
Original
Original
<p style="text-align: left"></p>
<p style="text-align: justify;"><strong>Introduction:</strong> Several studies have conducted on impairments of executive functions in individuals with methamphetamine addiction; however, only a few have investigated the relationship between executive functions and duration of addiction or abstinence. This study was designed to assess the executive functions in methamphetamine-addicted individuals in relation to the duration of addiction or abstinence.<br>
<strong>Methods:</strong> A total of 161 subjects aged between 20 and 45 years were categorized into three subgroups: currently abusing (n = 41), abstinent (n = 60), and control healthy individuals (n = 60). A battery of standardized executive function tasks, including Stroop test, Wisconsin Card Sorting test, and Tower of London task, were administered. Data were analyzed using Pearson correlation coefficient, analysis of variance, and post hoc Bonferroni test with SPSS16.0.<br>
<strong>Results:</strong> Methamphetamine-addicted and abstinent subjects performed worse than the controls. Methamphetamine-abstinent subjects performed better than the currently methamphetamine abusers in most executive functions. Duration of addiction and abstinence were correlated with executive dysfunctions.<br>
<strong>Conclusion:</strong> This study revealed that although executive functions may be improved by protracted abstinence, executive dysfunctions are not completely relieved, and specific attention to planning and implementation of intervention programs are necessary.</p>
Addiction, Abstinence, Methamphetamine, Executive function, Assessment
147
154
http://bcn.iums.ac.ir/browse.php?a_code=A-10-563-1&slc_lang=en&sid=1
Majid
Farhadian
majidfarhadian@yahoo.com
1370031947532846009817
1370031947532846009817
No
Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Malahat
Akbarfahimi
akbarfahimi.m@iums.ac.ir
1370031947532846009818
1370031947532846009818
Yes
Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Peyman
Hassani Abharian
abharian1972@yahoo.com
1370031947532846009819
1370031947532846009819
No
Department of Cognitive Rehabilitation, Institute for Cognitive Sciences Studies (ICSS), Tehran, Iran.
Seyedeh Golaleh
Hosseini
golalehossieni@yahoo.com
1370031947532846009820
1370031947532846009820
No
Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Susan
Shokri
Susan.Shokri@gmail.com
1370031947532846009821
1370031947532846009821
No
Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.