Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1391
11
1
gregorian
2013
2
1
4
1
online
1
fulltext
en
Septo-Hippocampo-Septal Loop and Memory Formation
Cellular and molecular Neuroscience
Cellular and molecular Neuroscience
Original
Original
<p>The Cholinergic and GABAergic .bers of the medial septal/diagonal band of Broca (MS/DB) area project to the hippocampus and constitute the septo-hippocampal pathway, which has been proven to play a role in learning and memory. In addition, the hippocampus has bidirectional connections with the septum so that to self-regulate of cholinergic input.</p>
<p>The activity of septal and hippocampal neurons is modulated by several neurotransmitter systems including glutamatergic neurons from the entorhinal cortex, serotonergic .bers from the raphe nucleus, dopaminergic neurons from the ventral tegmental area (VTA), histaminergic cells from the tuberomammillary nucleus and adrenergic .bers from the locus coeruleus (LC). Thus, changes in the glutamatergic, serotonergic and other systems- mediated transmission in the MS/DB may in.uence cholinergic or GABAergic transmission in the hippocampus.</p>
septo-hippocampal, septum, hippocampus, learning, memory
5
23
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-135&slc_lang=en&sid=1
Fatemeh
Khakpai
1370031947532846006493
1370031947532846006493
Yes
Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
Mohammad
Nasehi
1370031947532846006494
1370031947532846006494
No
Department of Biology, Faculty of Basic Sciences, Islamic Azad University, Garmsar Branch, Semnan, Iran.
Ali
Haeri-Rohani
1370031947532846006495
1370031947532846006495
No
Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
Akram
Eidi
1370031947532846006496
1370031947532846006496
No
Institute for Cognitive Science Studies (ICSS), Tehran, Iran.
Mohammad Reza
Zarrindast
1370031947532846006497
1370031947532846006497
No
Institute for Cognitive Science Studies (ICSS), Tehran, Iran.