Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1402
6
1
gregorian
2023
9
1
14
5
online
1
fulltext
en
Examining the Dominant Presence of Brain Grey Matter in Autism During Functional Magnetic Resonance Imaging
Clinical Neuroscience
Clinical Neuroscience
Review
Review
<div style="text-align: justify;"><strong>Introduction</strong>: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with symptoms appearing from early childhood. Behavioral modifications, special education, and medicines are used to treat ASD; however, the effectiveness of the treatments depends on early diagnosis of the disorder. The primary approach in diagnosing ASD is based on clinical interviews and valid scales. Still, methods based on brain imaging could also be possible diagnostic biomarkers for ASD. <br>
<strong>Methods</strong>: To identify the amount of information the functional magnetic resonance imaging (fMRI) reveals on ASD, we reviewed 292 task-based fMRI studies on ASD individuals. This study is part of a systematic review with the registration number CRD42017070975.<br>
<strong>Results</strong>: We observed that face perception, language, attention, and social processing tasks were mainly studied in ASD. In addition, 73 brain regions, nearly 83% of brain grey matter, showed an altered activation between the ASD and normal individuals during these four tasks, either in a lower or a higher activation. <br>
<strong>Conclusion</strong>: Using imaging methods, such as fMRI, to diagnose and predict ASD is a great objective; research similar to the present study could be the initial step.</div>
Functional magnetic resonance imaging, Examinations and diagnoses, Autism
585
604
http://bcn.iums.ac.ir/browse.php?a_code=A-10-1774-3&slc_lang=en&sid=1
Seyed Amir Hossein
Batouli
batouli@sina.tums.ac.ir
13700319475328460046647
13700319475328460046647
No
Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Foroogh
Razavi
forooghrazavi@gmail.com
13700319475328460046648
0009-0006-3913-135X
No
Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Minoo
Sisakhti
mno.cs1369@gmail.com
13700319475328460046649
13700319475328460046649
No
Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Zeinab
Oghabian
z_oghabian@yahoo.com
13700319475328460046650
0009-0003-6071-0055
No
Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
Haady
Ahmadzade
haady.ahmadzade@gmail.com
13700319475328460046651
0009-0005-5733-7696
No
Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi
Tehrani Doost
tehranid@tums.ac.ir
13700319475328460046652
13700319475328460046652
Yes
Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.