Basic and Clinical Neuroscience Journal
مجله علوم اعصاب پایه و بالینی
BCN
Medical Sciences
http://bcn.iums.ac.ir
137
journal137
2008-126X
2228-7442
10.32598/bcn
en
jalali
1396
12
1
gregorian
2018
3
1
0
Accepted Articles
online
1
fulltext
en
Alteration of Brain Functional Network and Cortisol Level During Induction and Release of Stress: An EEG Study in Young Male Adults
Cognitive Neuroscience
Cognitive Neuroscience
Original
Original
Acute stress in a long period of time could drastically influence one's behavioral and cognitive performances. Therefore, it is important to control the stressful situation and release it after a stressful event. In this regard, understanding of brain mechanism of the stress release will help to introduce new practical approaches. In this study, we hypothesized that induction and release of stress will change the brain functional connectivity pattern. Therefore, by recruiting 20 healthy-subjects and exposing them to stressful events using the trier social stress paradigm, we aimed to investigate patterns of these changes. In a session consist of 23 minutes of psychological stress induction and 20 minutes of recovery, subjects' stress was scored by visual analogue scale (VAS). In addition, salivary cortisol level and EEG data of the subjects were also recorded. Subsequently, brain functional connectivity (FC) maps were calculated in a frequency-specific manner. Then, the effects of inducing and release of stress on the changes of VAS, cortisol level, and FC maps were assessed. Our results revealed that inter-hemispheric FCs of the right frontal regions with other regions of the brain decrease; while it increases at the left frontal regions during inducing of mental stress. Interestingly, the release of stress presented a recovery pattern of inter-hemispheric FCs and meaningful FC changes significantly correlate with changes in the cortisol level. our findings highlight important roles of bihemispheric associations in adaptation and coping with stressful conditions.
Stress, Visual analogue scale, Cortisol, EEG, Functional connectivity.
0
0
http://bcn.iums.ac.ir/browse.php?a_code=A-10-2525-1&slc_lang=en&sid=1
Zahra
Rezvani
z_rezvani@sbu.ac.ir
13700319475328460034543
13700319475328460034543
No
Institute for Cognitive and Brain Sciences, Shahid Beheshti University GC, Tehran, Iran.
Reza
Khosrowabadi
r_khosroabadi@sbu.ac.ir
13700319475328460034544
13700319475328460034544
No
Institute for Cognitive and Brain Sciences, Shahid Beheshti University GC, Tehran, Iran.
Afrooz
Seyedebrahimi
afrooz.seyedebrahimi@gmail.com
13700319475328460034545
13700319475328460034545
No
Institute for Cognitive and Brain Sciences, Shahid Beheshti University GC, Tehran, Iran.
Golam-Hossein
Meftahi
meftahi@sbmu.ac.ir
13700319475328460034546
13700319475328460034546
No
Neuroscience Research Center, Baqiyatallah University of Medical Science, Tehran, Iran.
Boshra
Hatef
boshrahatef@bmsu.ac.ir
13700319475328460034547
13700319475328460034547
Yes
Neuroscience Research Center, Baqiyatallah University of Medical Science, Tehran, Iran.