AU - Soleimani Asl, Sara AU - Pourheydar, Bagher AU - Dabaghian, Fataneh AU - Nezhadi, Akram AU - Roointan, Amir AU - Mehdizadeh, Mehdi TI - Ecstasy-Induced Caspase Expression Alters Following Ginger Treatment PT - JOURNAL ARTICLE TA - BCN JN - BCN VO - 4 VI - 4 IP - 4 4099 - http://bcn.iums.ac.ir/article-1-437-en.html 4100 - http://bcn.iums.ac.ir/article-1-437-en.pdf SO - BCN 4 ABĀ  - Introduction: Exposure to 3-4, methylenedioxymethamphetamine (MDMA) leads to cell death. Herein, we studied the protective effects of ginger on MDMA- induced apoptosis. Methods: 15 Sprague dawley male rats were administrated with 0, 10 mg/kg MDMA, or MDMA along with 100mg/kg ginger, IP for 7 days. Brains were removed to study the caspase 3, 8, and 9 expressions in the hippocampus by RT-PCR. Data was analyzed by SPSS 16 software using the one-way ANOVA test. Results: MDMA treatment resulted in a significant increase in caspase 3, 8, and 9 as compared to the sham group (p CP - IRAN IN - LG - eng PB - BCN PG - 329 PT - Original YR - 2013