دوره 9، شماره 2 - ( March & April 2018 1396 )                   جلد 9 شماره 2 صفحات 147-156 | برگشت به فهرست نسخه ها


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Shahveisi K, Jalali A, Moloudi M R, Moradi S, Maroufi A, Khazaie H. Sleep Architecture in Patients With Primary Snoring and Obstructive Sleep Apnea. BCN. 2018; 9 (2) :147-156
URL: http://bcn.iums.ac.ir/article-1-895-fa.html
Sleep Architecture in Patients With Primary Snoring and Obstructive Sleep Apnea. مجله علوم اعصاب پایه و بالینی. 1396; 9 (2) :147-156

URL: http://bcn.iums.ac.ir/article-1-895-fa.html


چکیده:  

Introduction: This study aimed to investigate sleep architecture in patients with primary snoring and obstructive sleep apnea.
Methods: In this study, we analyzed polysomnographic data of 391 clients who referred to Sleep Disorders Research Center (SDRS). These people were classified into three groups based on their Apnea-Hypopnea Index (AHI) and snoring; control, Primary Snoring (PS), and Obstructive Sleep Apnea (OSA) group. Sleep architecture variables were then assessed in all groups.
Results: The results of this study indicated a decrease in deep sleep or Slow Waves Sleep (SWS) and increase in light sleep or stage 1 of non-REM sleep (N1) in OSA patients compared with the control and PS groups. After controlling the effects of confounding factors, i.e. age and Body Mass Index (BMI) (which was performed through multiple regression analysis) significant differences were observed among the three groups with regard to N1. However, with regard to SWS, after controlling confounding variables (age and BMI), no significant difference was found among the groups.
Conclusion: The results indicated that OSA, regardless of age and BMI, may increase light (N1) sleep possibly via a decline in blood oxygen saturation (SpO2). Such increase in N1 may be responsible for brain arousal. In addition, by controlling confounding factors (age and BMI), OSA did not affect SWS in OSA patients. However, further research is necessary to determine sleep architecture in more detail in the patients with OSA.

نوع مطالعه: Original | موضوع مقاله: Clinical Neuroscience
دریافت: ۱۳۹۵/۱۰/۱۸ | پذیرش: ۱۳۹۶/۵/۵ | انتشار: ۱۳۹۶/۱۲/۱۲

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