دوره 8، شماره 4 - ( July & August 2017 -- 1396 )                   جلد 8 شماره 4 صفحات 337-343 | برگشت به فهرست نسخه ها




DOI: 10.18869/nirp.bcn.8.4.337

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Almasi M, Motamed M R, Mehrpour M, Haghi-Ashtiani B, Haji Akhondi F, Nilipour Y et al . A Mitochondrial Disorder in a Middle Age Iranian Patient: Report of a Rare Case. BCN. 2017; 8 (4) :337-343
URL: http://bcn.iums.ac.ir/article-1-710-fa.html
A Mitochondrial Disorder in a Middle Age Iranian Patient: Report of a Rare Case. مجله علوم اعصاب پایه و بالینی. 1396; 8 (4) :337-343

URL: http://bcn.iums.ac.ir/article-1-710-fa.html


چکیده:  

Introduction: Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) can involve multiple systems and cause stroke-like episodes and status epilepticus.
Case Presentation: A 48-year-old female with history of early fatigability, migraine-type headaches, and bilateral sensory-neural hearing loss presented 3 episodes of serial seizures. On admission she was affected by Wernicke aphasia and, then, right hemiparesis. Investigations showed elevated arterial lactate and ragged red fibers on muscle biopsy.
Conclusion: Though more commonly diagnosed during childhood, some cases of adult-onset MELAS syndrome are reported. This syndrome should be considered in patients with stroke-like events in adults without cerebrovascular risk factors and difficult-to-treat seizures.

نوع مطالعه: Original | موضوع مقاله: Cellular and molecular Neuroscience
دریافت: ۱۳۹۵/۸/۱۵ | پذیرش: ۱۳۹۵/۱۱/۳۰ | انتشار: ۱۳۹۶/۴/۱۰

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