دوره 10، شماره 1 - ( January & February 1397 )                   جلد 10 شماره 1 صفحات 72-59 | برگشت به فهرست نسخه ها


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Talimkhani A, Abdollahi I, Mohseni-Bandpei M A, Ehsani F, Khalili S, Jaberzadeh S. Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study. BCN 2019; 10 (1) :59-72
URL: http://bcn.iums.ac.ir/article-1-1057-fa.html
Differential Effects of Unihemispheric Concurrent Dual-Site and Conventional tDCS on Motor Learning: A Randomized, Sham-Controlled Study. مجله علوم اعصاب پایه و بالینی. 1397; 10 (1) :59-72

URL: http://bcn.iums.ac.ir/article-1-1057-fa.html


چکیده:  
Introduction: Based on the literature, unihemispheric concurrent dual-site anodal transcranial Direct Current Stimulation (a-tDCSUHCDS) of primary Motor cortex (M1) and Dorsolateral Prefrontal Cortex (DLPFC) would be more efficient than conventional a-tDCS of M1 to induce larger and longer-lasting M1 corticospinal excitability. The main objective of the present study was to compare the effects of a-tDCSUHCDS and conventional M1 a-tDCS on the extent and durability of the motor sequence acquisition in healthy individuals.
Methods: In this randomized sham-controlled study, healthy volunteers were randomly divided into three groups: experimental (a-tDCSUHCDS), control (M1 a-tDCS), and sham stimulation groups. The participants practiced serial response time task over three consecutive days when they simultaneously received a-tDCS. Using the skill measure, we assessed motor learning up to 4 weeks after the completion of experimental conditions. 
Results: Data analysis revealed that all groups exhibited the improved trend over the training course (P<0.001). There were no significant differences in skill acquisition among groups at post-intervention (P>0.05), while a significant improvement was observed between experimental and sham group at the retention time (P<0.05). Moreover, there were no significant differences between the control and two other groups with regard to the retention time (P>0.05). 
Conclusion: These results revealed a significant increase in the skill acquisition by a-tDCSUHCDS technique with regard to retention issue, which could be a valuable finding in neuro-rehabilitation field. 
نوع مطالعه: Original | موضوع مقاله: Clinical Neuroscience
دریافت: 1396/8/6 | پذیرش: 1397/2/10 | انتشار: 1397/10/11

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